What is the Longevity Foundations Panel?

The Longevity Foundations Panel is an early-intervention blood test designed to uncover silent biological ageing processes long before clinical disease develops. Rather than reacting to symptoms, this panel focuses on core pathways known to accelerate ageing, cardiovascular risk, and metabolic decline.

It is ideal as a starting point for longevity optimisation, healthspan tracking, and preventative strategies, even in people who feel “well” on the surface.

Core purpose of the panel

Identify silent ageing drivers before symptoms appear.

Modern ageing is often driven by low-grade inflammation, impaired methylation, metabolic stress, and dysregulated growth signalling. These changes can be present for years before diagnosis of cardiovascular disease, diabetes, or neurodegeneration.

This panel highlights those risks early, allowing corrective action when it matters most.

What does the panel include?

Key longevity drivers

Homocysteine
A marker of methylation efficiency and vascular ageing. Elevated levels are linked to cardiovascular disease, cognitive decline, and accelerated biological ageing.

IGF-1
Reflects growth signalling balance. Excessive IGF-1 may accelerate ageing, while low levels may impair repair and resilience. This marker helps assess the growth vs longevity trade-off.

hs-CRP
A highly sensitive inflammation marker. Even mildly elevated levels indicate chronic low-grade inflammation, a major driver of ageing and disease.

Supporting health markers

Full Blood Count
Provides insight into immune health, oxygen delivery, and systemic stress.

Liver Function Tests
Ensures metabolic processing and detox capacity are functioning optimally.

Lipid Profile
Total Cholesterol, HDL, LDL, Triglycerides – assesses cardiovascular and metabolic risk.

Glucose Control
HbA1c and fasting glucose – identifies early insulin resistance and glycaemic stress.

Methylation & repair nutrients
Vitamin B12 and Folate – essential for DNA repair, methylation, and homocysteine control.

Why do I need a Longevity Foundations Panel?

Ageing rarely starts with symptoms. The earliest changes occur at a biochemical level.

This panel is recommended if you:

• Want to optimise healthspan, not just lifespan
• Have a family history of cardiovascular or metabolic disease
• Are interested in preventative, data-driven longevity
• Want a baseline before deeper longevity or peptide testing
• Feel “fine” but want to identify hidden risks
• Are managing stress, inflammation, or metabolic health

Common hidden drivers this panel can uncover:

• Chronic low-grade inflammation
• Impaired methylation
• Early insulin resistance
• Unfavourable lipid patterns
• Growth signalling imbalance

Benefits of the test

1. Identifies ageing drivers before disease

2. Detects silent cardiovascular risk

3. Assesses growth vs longevity balance

4. Highlights chronic inflammation early

5. Supports personalised longevity strategies

6. Establishes a clear biological baseline

7. Guides targeted nutrition and lifestyle changes

8. Enables long-term healthspan tracking

Expanded benefit explanation
By targeting the root biochemical processes of ageing, this panel allows early intervention at a stage where changes are most reversible.

Step-by-step — How testing works

We offer two UK-wide options:

Clinic testing
• Choose your nearest UK clinic
• Blood sample taken by a clinician
• Samples analysed by an accredited laboratory
• Results delivered securely

Home visit (+£60)
• Phlebotomist visits your home or hotel
• Blood drawn safely and professionally
• Samples sent to laboratory
• Results delivered securely

Both services are available UK-wide.

Your results explained

Sub-optimal markers

May indicate early vascular ageing, inflammation, metabolic stress or impaired methylation requiring optimisation.

Optimal ranges

Suggest a favourable longevity profile with balanced repair and growth signalling.

Elevated risk markers

Highlight areas where lifestyle, nutrition or clinical intervention may significantly reduce long-term disease risk.

UK laboratory reference ranges are provided with all results.